A study shows that a twice-yearly shot was 100% effective in preventing new HIV infections in women in Africa.

U.S. stock indexes closed mostly higher Friday, though the S&P 500 posted its first weekly loss in four weeks. Treasury yields remained near their highest levels since June. Before this week, the S&P 500 had notched a weekly gain three weeks in a row. American Express fell 3.6% and chipmaker Intel sank 10.6%, the biggest decline in the S&P 500, after reporting weakness in its data center business. Treasury yields dipped but remain near their highest levels since June.

NEW YORK – When she learned that Ethan Hawke was working on a special audio edition of her acclaimed novel “Gilead,” Marilynne Robinson's response was to get a better idea of who he was. Winner of the Pulitzer Prize in 2005, ”Gilead” is the first of four Robinson novels set in a rural Iowa community in the 1950s. Hawke has recorded an abridged narrative of “Gilead” that was commissioned by Manhattan's 92nd Street Y and can he heard Oct. 19-29 via www.92y.org/gilead. “In ‘Gilead,’ the Reverend John Ames contemplates ‘grace as a sort of ecstatic fire that takes things down to essentials,'" he said. ‘Gilead' is a great American novel, and Ethan Hawke is a great American actor."

The governor’s office said Newsom was tested on Wednesday after someone in the governor’s office tested positive. The staff member who tested positive had not interacted with Newsom or anyone else who often sees the governor. ___HARTFORD, Conn. -- Dr. Deborah Birx of the White House coronavirus task force says she is concerned about the uptick in coronavirus cases in the Northeast. The virus has killed at least 5,416 people in Louisiana, according to the state health department. A cluster of fewer than 20 people tested positive for the virus at the Nashville Rescue Mission’s facility for women and children, Brian Todd said.

PEMBROKE PINES, Fla. – Family, friends and colleagues of a beloved elementary school teacher are hoping for a miracle for Stefanie Miller. But at Memorial West, where Miller is being treated, the hospital is not one that was selected by the federal government or Gilead to give her the drug. Memorial West was not one of the hospitals chosen by the federal government or Gilead. Memorial Regional in Hollywood, is one of them, but not Memorial West. Miller, a second-grade teacher at Fox Trail Elementary in Davie, was working from her hospital bed up until recently.

MIAMI-DADE COUNTY, Fla. – A Florida resident was diagnosed with the new coronavirus, also known as COVID-19, in Washington state, authorities said on Wednesday. Ron DeSantis said the patient, who is in isolation, “had been traveling in Asia, probably in China.” The Centers for Disease Control considers this a Florida case even though the diagnosis was in Washington, DeSantis said. A New York man who had recently traveled to Miami was diagnosed with the coronavirus, Gov. One Florida patient is in Manatee County and the other two Florida patients -- who were diagnosed after traveling to Italy -- are in Hillsborough County. Fauci also told the Senate on Tuesday that pharmaceutical company Gilead is testing a potential treatment.