San Francisco 49ers coach Kyle Shanahan started training camp with a declaration that second-year player Trey Lance will be the starting quarterback and Jimmy Garoppolo will be moving on soon.

James Conner ran for two touchdowns and caught a 45-yard TD pass from backup quarterback Colt McCoy as the short-handed Arizona Cardinals beat the San Francisco 49ers 31-17.

Still, short-handed San Francisco had enough to beat the inept New York Jets. Defensive end Nick Bosa and defensive tackle Solomon Thomas were both carted off the field two plays apart with left knee injuries in the first quarter. Two plays later, Thomas was carted off — also with a left knee injury — after an 8-yard reception by Chris Hogan. San Francisco ended the 14-play possession with an 18-yard catch by Jordan Reed for the first of his two TD grabs. ... San Francisco wide receiver Brandon Aiyuk, a first-round draft pick, had two catches for 21 yards in his NFL debut.