The Buffalo Bills stand to open the season minus two new free-agent defensive line additions upon learning Larry Ogunjobi and Michael Hoecht both face six-game suspensions for violating the NFL’s performance-enhancing drugs policy.

The Buffalo Bills made the long-anticipated salary cap-saving decision to release edge rusher Von Miller, according to a person with knowledge of the decision.

The Buffalo Bills on Friday reached an agreement to sign starting middle linebacker Terrel Bernard to a four-year contract extension worth up to $50 million, with $25.2 million of it guaranteed, in locking up their defensive leader through the 2029 season.

Buffalo Bills general manager Brandon Beane opened training camp by firing back at an anonymous critic of quarterback Josh Allen.

English rugby player turned offensive tackle prospect Travis Clayton's dream of playing in the NFL took a major step forward after the Buffalo Bills selected him in the seventh round of the NFL draft.

The Buffalo Bills’ salary cap-related purge of players cut deep into the team’s core.

Buffalo Bills general manager Brandon Beane is disappointed in the allegations of domestic violence made against Von Miller, while stressing he and the team are waiting for the legal process to play out rather than rush to judgement.

With a helmet on, Buffalo Bills safety Damar Hamlin took part in team drills in a practice open to reporters for the first time in six months since having a near-death experience during a game.

Buffalo Bills safety Damar Hamlin says his doctors have concluded a hit to the chest caused his heart to stop after a tackle in January.

The Buffalo Bills’ top pass-rusher Von Miller will miss the remainder of the season after having surgery to repair an injury to the anterior cruciate ligament in his right knee.

The NFL is relocating the Bills' home game against the Cleveland Browns to Detroit on Sunday because of a lake-effect snowstorm set to hit the Buffalo region.

In the face of a major public backlash and internal questions over the decision to award Matt Araiza the punting job, the Buffalo Bills reversed course by cutting the rookie on Saturday, two days after a lawsuit was filed alleging the player and two college teammates gang-raped a teenager last fall.

Receivers Cole Beasley and Gabriel Davis are among four Buffalo Bills players who must spend at least five days away from the team facility after having close contact with a trainer who tested positive.

A person with direct knowledge of the NFL's directive tells The Associated Press a team can't release a player simply because he is not vaccinated for COVID-19.

Buffalo Bills general manager Brandon Beane would theoretically consider cutting an unvaccinated player if it meant the team being able to lift NFL COVID-19 protocols restricting in-person team meetings.

Buffalo Bills quarterback Josh Allen and linebacker Tremaine Edmunds are staying around for at least two more seasons.