SUNRISE, Fla. ā More than 106,000 cases of colorectal cancer are expected to be diagnosed in the United States in 2022 and while screening is recommended beginning at age 45, some people need to start much sooner due to underlying genetic conditions.
When Cheri Prybyl went for her annual mammogram in 2018, the technician found her family history āinteresting.ā
āThe technician, after I was done, said, āWow there seems to be a lot of cancer on your momās side of the family ā on the maternal side of the family.ā Have you ever thought about having genetic testing?ā Prybyl said.
Genetic testing revealed Prybyl had a condition called Lynch Syndrome, which elevated her risk for a variety of cancers including colon cancer.
āIf your parent has it, if you have a family member that has it, you have a risk of inheriting this condition where your genes, they just kind of, theyāre unable to repair damages in your DNA,ā said Dr. Brenda Jimenez, a gastroenterologist with Cleveland Clinic Weston.
While the risk of colon cancer by age 50 in the general population is well below one percent, in people with Lynch Syndrome, itās 25 percent.
āItās mentioned that approximately three to five percent of all colorectal cancers are secondary to Lynch Syndrome,ā Jimenez said.
Having lost members of her family to colorectal cancer, Prybyl made sure everyone on her side of the family, including her own children got tested.
āI have the tools, I have the knowledge to be proactive and not say, āOh, Iām not going to get this done right now. Itās not comfortable doing a colonoscopy but itās preventive and itās lifesaving,ā she said.
Prybylās sister, niece and nephew and both of her daughters tested positive for Lynch Syndrome.
Her youngest daughter Rachel had an aggressive colon polyp removed at the age of 23.
āThat really kind of shocked me that I need to be on top of scheduling my colonoscopies because this could potentially be scary if I donāt do this,ā Prybyl said.
Lynch Syndrome also increases the risk of endometrial cancer, including cancer of the uterus and ovaries.