Five games ended with game-winning field goals in regulation Sunday, the most in one day in NFL history.

Marco Wilson and Isaiah Simmons scored touchdowns on two pick-6s late in the first half and used that stunning change in momentum to lift the Arizona Cardinals over the New Orleans Saints 42-34.

Jalen Hurts ran for two touchdowns and the Philadelphia Eagles remained the NFL’s only unbeaten team, beating Arizona 20-17 on Sunday after Matt Ammendola’s late field-goal attempt for the Cardinals sailed wide right.

Carson Wentz threw a pair of touchdown passes, Jonathan Taylor ran for 108 yards and the banged-up Indianapolis Colts continued their late-season surge with a gritty 22-16 win over the Arizona Cardinals on Saturday night.

Matthew Stafford threw for 287 yards and three touchdowns, Cooper Kupp and Odell Beckham Jr. each caught a touchdown pass and the Los Angeles Rams held on for a 30-23 win over the Arizona Cardinals.

From Lamar Jackson’s improbable comeback that ended in an overtime win for Baltimore to the missed kick festival between Green Bay and Cincinnati, the NFL had several more games go down to the wire in Week 5.

The Arizona Cardinals improved to 5-0 for the first time since 1974, riding a stellar defensive performance to a 17-10 win over the San Francisco 49ers on Sunday.

Matt Ryan threw for 342 yards and two touchdowns including the first NFL score for Kyle Pitts and the Atlanta Falcons held on and closed out the New York Jets in a 27-20 victory in the NFL’s return to London.

Kyler Murray threw for 400 yards and three touchdowns, and the Arizona Cardinals topped the Minnesota Vikings 34-33 after Greg Joseph missed a 37-yard field goal wide right in the final seconds.

Kyler Murray scored five touchdowns and linebacker Chandler Jones had a career-high five sacks as the Arizona Cardinals simply dominated the Tennessee Titans 38-13 for a big road win to open the season.

Matt Prater kicked two field goals in the final two minutes, including a 47-yard game winner with no time remaining, to lift the Arizona Cardinals over the Dallas Cowboys 19-16 on Friday night in a preseason game.

FILE - Chicago Bears quarterback Mitchell Trubisky throws a pass during an NFL football game against the Minnesota Vikings in Minneapolis, in this Sunday, Dec. 20, 2020, file photo. Now that the muzzles have been removed for NFL team executives and the players they either re-signed or added in free agency, Thursday was a time for explanations and reflections. New England bringing back LB Kyle Van Noy, Buffalo grabbing QB Mitchell Trubisky, and Tennessee getting All-Pro long snapper Morgan Cox. Green), players staying put (Leonard Williams, Derek Wolfe) and even a player coming out of retirement (Kyle Long). He played 14 games with eight starts for Baltimore after signing a $3 million contract to join the team from Denver.

Henry came into Sunday’s regular season finale needing 223 yards rushing to become the second man in franchise history to reach 2,000. He came in as the NFL’s rushing leader for a second straight season with a career-best 1,777 yards rushing. The Green Bay Packers have set an NFL season record for second-quarter points. With the run Newton also passed Grogan for the single-season team record for rushing yards by a quarterback. Newton entered the game 26 yards behind Grogan, who had 539 rushing yards in 1978.

Green Bay Packers quarterback Aaron Rodgers throws during the first half of an NFL football game against the Detroit Lions, Sunday, Dec. 13, 2020, in Detroit. Rodgers ran for a tiebreaking score in the third quarter and threw three touchdown passes, lifting the Green Bay Packers to a 31-24 win over the the Detroit Lions to clinch the NFC North title. “To have the whole thing come through Green Bay is something we’ve talked about for a long time," Rodgers said. “That would definitely be in our favor with the weather that we have in Green Bay. Green Bay repeated as division champion with its win and Minnesota’s loss to Tampa Bay earlier in the day.

Cleveland Browns running backs Nick Chubb (24) and Kareem Hunt (27) walk off the field after an NFL football game, Sunday, Nov. 15, 2020, in Cleveland. A win is a win; let Las Vegas worry about the margin of victory. It appeared there were actually 10 seconds left when down judge Dana McKenzie blew his whistle and raised his left hand. There actually should have been only 4 seconds left, which probably would have forced a Hail Mary by Stafford. But with 6 seconds left, Stafford had time for a quick pass, and he hit Marvin Jones for 9 yards.

(AP Photo/Tony Ding)DETROIT – Matt Prater made a 59-yard field goal as time expired, lifting the Detroit Lions to a 30-27 win over Washington on Sunday. Stafford threw a 9-yard pass to Marvin Jones to set up the kick. Washington (2-7) pulled into a tie by scoring touchdowns on three straight series in the second half in Alex Smith's first start in nearly two years. In the second half, Washington got into the end zone on 82- and 84-yard drives and had the ball midway through the fourth quarter down a touchdown. Lions: WR Kenny Golladay (hip) missed his second straight game and has played just five times this season because of different injuries.

Detroit Lions defensive end Trey Flowers (90) celebrates during the second half of an NFL football game against the Atlanta Falcons, Sunday, Oct. 25, 2020, in Atlanta. (AP Photo/Brynn Anderson)

Detroit Lions wide receiver Kenny Golladay (19) makes the catch against Atlanta Falcons cornerback A.J. (AP Photo/John Bazemore)ATLANTA – The Lions let the Falcons score a touchdown. Matthew Stafford connected with T.J. Hockenson on an 11-yard touchdown pass as time expired and Matt Prater booted a 48-yard extra point to give Detroit an improbable 23-22 victory over Atlanta on Sunday. The Lions (3-3) won their second in a row — their first winning streak since early in the 2019 season. Touchdown, Lions.

Detroit Lions quarterback Matthew Stafford throws against the Chicago Bears in the first half of an NFL football game in Detroit, Sunday, Sept. 13, 2020. (AP Photo/Duane Burleson)DETROIT – Mitchell Trubisky perfectly lofted a 27-yard go-ahead touchdown pass to Anthony Miller with 1:54 remaining and the Chicago Bears held on to beat the Detroit Lions 27-23 Sunday. Trubisky threw three touchdown passes in the fourth quarter to help Chicago come back from a 17-point deficit. It looked familiar to Lions fans: Detroit opened last season by blowing an 18-point lead at Arizona and settling for a tie. Late in the game, Lions fans likely would've filled the facility with a chorus of boos.